CBBS Members

During his tenure, Prof. Gundelfinger focused on the molecular and cellular mechanisms of synaptic plasticity in the healthy brain and their dysfunctions in the diseased brain. Communication between nerve cells takes place at microscopically small connections called synapses. During the wiring of the brain, synapses must form; afterwards, they must be maintained in a functional state and, for example, remodeled during learning and memory processes. Many molecules in the neurons, on their surfaces, and in the surrounding extracellular matrix are involved in these processes. In the various closely cooperating working groups of the department, the functioning of synapses, their molecular composition, and their plasticity under normal physiological conditions and in disease-related dysregulation are investigated.